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Issue Dairy Sci. Technol.
Volume 89, Number 3-4, May-August 2009
1st IDF/INRA International Symposium on Minerals and Dairy Products
Page(s) 233 - 239
DOI 10.1051/dst/2009011
Published online 24 March 2009

Dairy Sci. Technol. 89 (2009) 233-239
DOI: 10.1051/dst/2009011

Note

The inhibitory effect of glycomacropeptide on dental erosion

Anita Setareh Nejad , Ara Kanekanian and Arthur Tatham

Cardiff School of Health Sciences, University of Wales Institute Cardiff, Western Avenue, Cardiff CF5 2YB, UK

Received 3rd October 2008 - Accepted 18 February 2009 - / Published online 24 March 2009

Abstract - Throughout the world, the consumption of acidic foods, soft drinks and fruit juices has increased and has been associated with a rise in dental problems such as caries and erosion. The aim of this study was to investigate the protective effect of glycomacropeptide (GMP) against dental erosion and to compare the effect with that of caseinophosphopeptides (CPP). To assess the contribution of the calcium content of these peptides and their protection, calcium-reduced GMP (GMP-ca) and calcium-reduced CPP (CPP-ca) were studied. Hydroxyapatite was used as the tooth model. At a pH of 3, the protective effect of GMP was superior to that of CPP; however, CPP performed better at a pH of 4.5. The effect of GMP-ca and CPP-ca was evident only at a pH of 4.5, when compared with native GMP and CPP. These findings indicate that the calcium content of the peptide may have a role in protection against mineral loss from teeth. However, the pH of the erosive solution was the most influential factor contributing to erosion.


Résumé - Effet inhibiteur du glycomacropeptide sur l'érosion dentaire.
La consommation mondiale d'aliments acides, de boissons non alcoolisées et de jus de fruit a augmenté et a été associée à l'élévation des problèmes dentaires tels que caries et érosion. Le but de cette étude a été d'examiner l'effet protecteur du glycomacropeptide (GMP) envers l'érosion dentaire et de le comparer à celui des caséinophosphopeptides (CPP). De plus, pour évaluer la contribution de la teneur en calcium de ces peptides à leur effet protecteur, des GMP et CPP à teneur réduite en calcium ont été également étudiés. L'hydroxyapatite a été utilisée comme dent modèle. À pH 3, l'effet protecteur du GPM était supérieur à celui du CPP. Le CPP donnait cependant de meilleurs résultats à pH 4,5. L'effet de la réduction du calcium était évident seulement à pH 4,5 par comparaison aux GPM et CPP natifs. Ces résultats indiquent que la teneur en calcium du peptide peut avoir un rôle dans la protection contre la perte minérale des dents. Cependant, le pH de la solution érosive est le facteur d'influence majeur contribuant à l'érosion.


Key words: glycomacropeptide / caseinophosphopeptide / calcium / dental erosion

Mots clés : glycomacropeptide / caséinophosphopeptide / calcium / érosion dentaire

Corresponding author: ansetarehnejad@uwic.ac.uk akanekanian@uwic.ac.uk

© INRA, EDP Sciences 2009


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